【摘 要】
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Objective: To investigate Monocarboxylate transporter 4 (MCT4) expression in oral squamous cell carcinoma (OSCC) patients and its role in cancer maintenance and aggressiveness.Methods: The MCT4 expres
【机 构】
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Institute of Stomatology & Department of Oral and Maxillofacial Surgery,Affiliated Hospital of Stoma
【出 处】
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11th Asian Congress on Oeal and Maxillofacial Surgery(第十一届亚洲
论文部分内容阅读
Objective: To investigate Monocarboxylate transporter 4 (MCT4) expression in oral squamous cell carcinoma (OSCC) patients and its role in cancer maintenance and aggressiveness.Methods: The MCT4 expression in 99 cases of OSCC was examined by immunohistochemistry.Based on these patients information and their follow-up data, the correlations of the MCT4 level with patients clinicopathological characteristics and prognosis were further evaluated by statistical analyses using Fisher exact test and Kaplan-Meier method respectively.To further study mechanisms of MCT4 in vitro, we used small-interfering RNA to silence its expression in OSCC cell lines.
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