【摘 要】
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Alginate(SA) and chitosan(CS) are commonly used natural polysaccharides.Their well-known biological properties such as biocompatibility, non-toxicity, non-immune prototype and high hydrophilicity make
【机 构】
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School of Materials Science and Engineering, Shanghai University, Shanghai 200444
【出 处】
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第十五届上海地区医用生物材料学术研讨会
论文部分内容阅读
Alginate(SA) and chitosan(CS) are commonly used natural polysaccharides.Their well-known biological properties such as biocompatibility, non-toxicity, non-immune prototype and high hydrophilicity make the two kinds of biomaterials exhibit remarkable performance in tissue engineering.In our work, polyelectrolyte complex scaffolds composed of alginate and chitosan were fabricated by electrostatic interaction between-COO-and-NH3+ groups.Porous structure was achieved through phase separation technique.By varying the molar ratio (-COO-/-NH3+), the scaffolds presented elastic behavior and fatigue durability by cyclic mechanical test in wet state.In vitro, rabbit adipose-derived stem cells (rASCs) culture indicated that more CS content resulted in more adherent cells in the SA/CS scaffolds.
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