【摘 要】
:
Stroke is the second leading cause of death in industrialized countries.Despite tremendous research effort there is still only one approved therapy for acut
【机 构】
:
Department of Neurology University of Wuerzburg Germany
【出 处】
:
中国上海第七届国际新药发明科技年会
论文部分内容阅读
Stroke is the second leading cause of death in industrialized countries.Despite tremendous research effort there is still only one approved therapy for acute ischemic stroke that is thrombolysis using recombinant tissue plasminogen acticator (rt-PA).However,only a small number of patients are amenable to this treatment because application of rt-PA is restricted to the first 3h after stroke onset.Moreover,all substances used for the prevention of cerebral ischemia such as warfarin or acetyl salicyl acid (ASA) bear an increased risk of symptomatic bleeding.Thus,there is an unmet need for more effective and safer strategies to treat ischemic stroke.
其他文献
请下载后查看,本文暂不支持在线获取查看简介。中州黄荆盆景@李昊
Please download to view, this article does not support online access to view profile. Zhongzhou Hua
本文对生产和使用CCl_4和氯乙烯的工人进行了肝功能和肾上腺皮质功能检测。结果表明,工人长期在较高浓度的CCl_4和氯乙烯车间劳动,接触CCl_4工人的血浆皮质醇水平降低占25.9%
Human organic anion transporter hOAT1 plays a critical role in the body disposition of clinically important drugs.To investigate the role of transmembrane s
Accumulation of amyloid-β (Aβ) peptide is a pathological hallmark of Alzheimers disease (AD).Reduction of Aβ is believed to be a promising approach for t
廖志峰教授是甘肃省名中医,第四、五、六届全国老中医学术继承工作指导老师,从事中医临床工作五十余年,擅长治疗内科疑难杂病,学验俱丰.基于对廖志峰教授学术思想的研究,总结
本文通过实验研究和连续三年的劳动卫生学调查,结果表明,二氯甲烷属低毒类物质,对动物有一定的遗传效应,但无明显的致畸及胚胎毒作用;对长期接触一定浓度的作业工人可出现较
目的:研究夏枯草-菊花轮作模式栽培技术、经济效益.方法:田间试验介绍了湖北大别山区夏枯草-菊花轮作种植的栽培技术,分析了夏枯草-菊花轮作种植经济效益.结果:轮作模式效益
Today,the pharmaceutical industry is restructuring dramatically and rather painfully.During this time ofchange,innovative new models for research and busine
Eli Lilly and Company is a global pharmaceutical company with extensive capabilities and expertise in the development of small and large molecule (e.g.,anti
Loss of muscle mass occurs in aging,a variety of diseases,including cancer,chronic heart failure,aquired immunodeficiency syndrome,diabetes,and renal failur