2. 您的位置
3. 首页
4. 会议论文
5. Hepatocellular carcinoma targeted and redox-responsive glucolipid conjugate micelles for intracellul

Hepatocellular carcinoma targeted and redox-responsive glucolipid conjugate micelles for intracellul

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：mumuww

【摘 要】

：

Redox-responsive drug delivery system based on the difference redox environments between extra-and intra-cellular (100-1000 folds) and the same as the tumor cells and normal cells(7-10 folds),which ma

【作 者】

：

Na Liu Yanan Tan Hong Yuan Fuqiang Hu 

【机 构】

：

College of Pharmaceutical Sciences, Zhejiang University,866 Yuhangtang Road, Hangzhou 310058,P.R.Chi

【出 处】

：

2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会

【发表日期】

：

2015年9期

【关键词】

：

Redox-responsive Active targeting A54 peptide Control release 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Redox-responsive drug delivery system based on the difference redox environments between extra-and intra-cellular (100-1000 folds) and the same as the tumor cells and normal cells(7-10 folds),which makes it quickly and efficiently drug release at the target site.

其他文献

Construction and mechanism of a novel redox-responsive paclitaxel conjugate for efficacy intracellul

Polymer-drug conjugates have demonstrated significant potentials for the delivery of active agents to targets with minimal burst effect during transition.In this study a new bioconjugate HA-ss-PTX was

会议

Redox-responseHA-ss-PTX conjugatesActive tumor targetingIntracellular drug re

Preparation and characterization of lutein nanosuspensions

Background: Lutein (LUT), as an antioxidant agent, is widely used in food, nutraceutical and pharmaceutical products, but its poor solubility potentially restricted oral bioavailability of LUT.Objecti

会议

luteinanti-solvent precipitationnanosuspensionssolubility

Development of rotigotine loaded PLGA implants to achieve CDS for the treatment of PD

Continuous dopaminergic stimulation (CDS) has become the focus of the treatment strategy for Parkinsons disease (PD) that can prevent the development of dyskinesia[1].However, the currently available

会议

Doxorubicin-poly (ethylene glycol)-alendronate self-assembled micelles for targeted therapy of bone

Bone is a major organ of metastasis for many kinds of tumor, particularly for prostate and lung cancer.Although the bone metastasis of tumor is commonly not the major reason of death, symptoms associa

会议

poly(ethylene glycol) (PEG)pH-sensitivetumor-targeteddoxorubicin

The mitochondria-targeted and ICG-regulated theranosomes for in vivo imaging and enhanced photodynam

The applications of photodynamic therapy (PDT) were usually limited by low tumor selectivity of phtosensitizers.Herein, we reported an NIR imaging and mitochondria-targeted liposomes so called "theran

会议

The study on N-succinyl chitosan-poly-L-lysine-palmiti acid triblock polymers micelle deliveryed siR

Objective: Nowadays, RNA interference (RNAi) mediated by siRNA has rapidly become one of the standard tool for reversal of multidrug resistance.And the main difficulty of this is how to effectively im

会议

siRNAchitosan derivativeself-assembled micellesliver targeting

Optimization of the Freeze-dried Alprostadi-loaded Microemulsion

Objective: To optimize the prescription of freeze-dried Alprostadil-loaded microemulsion and study the influences on entrapment efficiency of freeze-dried Alprostadil-loaded microemulsion.Methods: Bas

会议

freeze-dried microemulsionconductivitypseudo-ternary phase diagram

Research of a novel ultra-fine particle processing system (UPPS)applied to prepare exenatide-loaded

Poly (D, L-lactic-co-glycolic acid) microparticles (PLGA-MPs) loading macromolecule are widely used as a long-acting delivery syster.However, current preparation methods have many disadvantages to pre

会议

Computer-aided analysis the mechanism of action between Mulberry alkaloid and glycosides by Molecula

Mulberry alkaloid, extracted from Chinese Medicine Mulberry, is one potential oral medication for treating type 2 diabetes by inhibiting Glycosides.Its pharmacologic activity has been studied thorough

会议

Nitinol stents loaded with a high dose of antitumor 5-fluorouracil or paclitaxel: In Vivo Evaluation

Background: Nitinol stents are widely used as a palliative treatment for malignant dysphagia, but many stents become obstructed because of tumor ingrowth.A number of researchers have been working on d

会议