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  5. IFN-γ is involved in apoptosis of trophoblast cells at the maternal-fetal interface following Toxopl

IFN-γ is involved in apoptosis of trophoblast cells at the maternal-fetal interface following Toxopl

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：zhyy3611
【摘 要】
：
Background: T.gondii is an extensive intracellular parasitic protozoon, which can infect all warm-blooded vertebrate species and lead to reproductive failure in the humans and animals.Moderate IFN-γ i
【作 者】
：
Xuemei Hu Ling Zhang 
【机 构】
：
Medicine & Pharmacy Research Center, Department of Immunology, Binzhou Medical College,Yantai, Shand
【出 处】
：
中国免疫学会第九届全国免疫学学术大会
【发表日期】
：
2014年8期
【关键词】
：
Toxoplasma gondii abnormal pregnancy outcomes apoptosis IFN-γ trophoblasts 
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Background: T.gondii is an extensive intracellular parasitic protozoon, which can infect all warm-blooded vertebrate species and lead to reproductive failure in the humans and animals.Moderate IFN-γ is essential for normal pregnancy,but more IFN-γmay induce abnormal pregnancy.In our previous study, result showed that IFN-γ expression was upregulated with T.gondii infection.However the underlying mechanism of IFN-γ induced abnormal pregnancy outcomes is still unclear.
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