The high prevalence of sleep disturbance has been found in patients with striatum-related neurodegenerative disorders.Striatum lesions in animals exhibited a 15% reduction in wakefulness.
Introduction: The ventral tegmental area (VTA) is crucial for brain functions, such as voluntary movement, cognition, emotion, reward, and motivation.However, the role of VTA in sleep-wake regulation
OBJECTIVE To elucidate the role and neural circuits of glutamatergic parabrachial nucleus (PB) neurons in the regulation of wakefulness.METHODS A chemogenetic approach was employed to clarify the elec
Sleep is regulated by two mechanisms, the homeostatic process and the circadian rhythm.Light affects sleep and alertness by entraining the circadian clock and inducing sleep/alertness acutely,which is
目的：通过临床观察证实二白汤治疗高血压伴失眠症的有效性.方法：通过对睡眠障碍专家门诊及中医科住院90例高血压伴失眠症病例,非随机临床分为两组,治疗组46例用二白汤治疗,对照组44例服用酒石酸唑吡坦片,两组对照比较治疗的有效率、治疗前后的国际通用SPIEGEL量衰减分率情况、中医症候变化及血压的变化情况、用药后的不良反应.结果：治疗组有效率为91.3％,对照组有效率为75.0％,两组比较有显著差异性
目的 研究中青年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的血清氧化应激水平和认知状况及两者的相关性，并评估持续气道正压通气(CPAP)对血清氧化应激程度及认知功能的影响。
Background: Our purpose was to investigate the relationship between oxygen saturation (SpO2) and dynamic interstitial glucose level (IGL) in patients with obstructive sleep apnea (OSA) along with type
目的：评价阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并基底节区脑卒中患者应用经鼻持续呼吸道正压通气(nCPAP)和(或)认知康复和(或)基础康复3种不同治疗措施对其睡眠、运动、认知、心理和日常生活能力的疗效.方法：共96例OSAHS合并基底节区脑卒中患者入选本研究，其中27例患者采用nCPAP+认知康复治疗12周；33例患者采用认知康复治疗；36例患者为对照.3组患者在治疗前、后均进行多导睡眠
目的 研究阻塞性睡眠呼吸暂停低通气综合征患者(OSAHS)的糖代谢及脂代谢指标变化，探讨OSAHS睡眠呼吸参数AHI及血氧饱和度＜90％时间占监测总时间的百分比(Ts90％)与糖脂代谢的相关性。方法 研究纳入334例疑似OSAHS患者，根据AHI分为单纯鼾症组、轻度OSAHS组、中度OSAHS组和重度OSAHS组，比较4组间甘油三脂(TG)、总胆固醇、HDL、LDL、空腹血糖(FPG)及糖化血红蛋
目的：评价疏阳益肝胶囊治疗伴阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的勃起功能障碍的疗效和安全性.方法：收集门诊350例OSAHS合并勃起功能障碍的患者,按照治疗方法分为3组,即单纯疏肝益阳胶囊治疗组、单纯持续正压通气治疗组及疏肝益阳胶囊联合持续正压通气治疗组,疗程4周.结果：单纯疏肝益阳胶囊治疗组,ED症状改