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Objective:To sum up the clinical experience of modified venous-arterial ultrafiltration (MUF) when it was applied to the cardiopulmonary bypass (CPB) in infants who underwent repair of congenital heart disease (CHD).Methods:From November 2004 to June 2007,the modified venous-arterial ultrafiltration was applied to 240 infants after cardiopulmonary bypass in our hospital.