T-ALL中miRNA及其靶基因GSK-3β的表达特点

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：mihu0907

【摘要】

：

目的：miR-29c,miR-92a,miR-125a/b以及miR-214与白血病的发生密切相关,其共同的靶基因GSK-3β广泛的参与了Notch、NF-κB、Wnt和Hedgehog等多种在白血病中异常活化信号通路。本研究探讨上述各miRNA及其靶基因GSK-3β在T细胞-急性淋巴细胞白血病(T-ALL)中的表达特点。

【作者】

：

徐艳周玲玲曾成武陆帅徐玲陈少华杨力建李菹罗更新李扬秋

【机构】

：

暨南大学再生医学教育部重点实验室暨南大学血液病研究所

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

T细胞-急性淋巴细胞白血病 miR-29c miR-92a miR-125a/b miR-214

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T-ALL中miRNA及其靶基因GSK-3β的表达特点

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