紫外线照射上调银屑病患者FOXP3转录因子的分子机制研究

来源 :中华医学会第二十次全国皮肤性病学术年会、国际特应性皮炎、皮肤病遗传、银屑病国际论坛 | 被引量 : 0次 | 上传用户:yuxume
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背景 紫外线照射(Ultraviolet Radiation,UVR)是临床上治疗银屑病的有效手段之一.抑制角质形成细胞的增殖和促进皮损效应性T细胞的凋亡是UVR作用的主要机制.近期研究表明,FOXP3+调节性T细胞与效应性T细胞之间免疫失衡是银屑病病情发展的中心环节之一.UVR是否对FOXP3+调节性T细胞具有调控作用及其分子机制尚无明确的结论.
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