Novel prognostic biomarkers of gastric cancer based on gene expression microarray:COL12A1,GSTA3,FGA

来源 :2019中国肿瘤学大会 | 被引量 : 0次 | 上传用户:beibeigou
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective Gastric cancer(GC)is the fifth most common malignancy in the world,especially in developing countries.GC has been the leading cause of cancer death worldwide until the mid-1990s,after which the occurrence has been substantially declining.
其他文献
Objective Acute myeloid leukemia(AML)is a malignant tumor of myeloid progenitor cells.It is characterized by the rapid growth of abnormal white blood cells in the bone marrow,which interferes with the
Objective colorectal cancer(CRC)is a common digestive system carcinoma,with characterized by highly local invasion and distant metastasis.Great attention has been increasingly paid to common signaling
目的 肿瘤细胞的生物学行为与其所处的微环境之间存在重要的关系。肿瘤细胞的快速增殖及肿瘤血管的异常,常常导致实体肿瘤中呈缺氧状态,以往我们认为缺氧主要影响肿瘤细胞的代谢和癌灶血管的重塑,但现在发现缺氧诱导因子在肿瘤的增殖、分化、侵袭转移产生重要的影响。
目的 真核起始因子4F(eIF4F)复合物可能在恶性肿瘤的形成和发展中发挥重要作用,该复合物由eIF4A、eIF4G 和eIF4E 组成。小分子化合物4EGI-1 是eIF4E 和eIF4G 相互作用的特异性抑制剂,本研究旨在探讨4EGI-1 对人胶质瘤U251 细胞线粒体功能的影响。
Objective Lung cancer still remains the leading cause of cancer-related deaths worldwide.About 85%of the lung cancers are non-small-cell lung cancer,including squamous cell carcinoma,adenocarcinoma,an
Objective Runt-Related Transcription Factor 1(RUNX1)is highly expressed in the Mes subtype of glioblastoma(GBM).The transforming growth factor-β(TGF-β)signaling pathway has been associated with a vari
Objective Circular RNAs(circRNAs)play important roles in the progression of cancers,but the precise role of circRNAs in the diagnosis and prognosis of hepatocellular carcinoma(HCC)remains to be clarif
目的 脑胶质瘤是最常见的原发神经系统恶性肿瘤,治疗困难,患者预后极差,急需寻找新的治疗方案。去泛素化酶广泛参与肿瘤增殖、侵袭等恶性进程,是潜在的抗肿瘤靶点。本项目旨在研究去泛素化酶UCH37 在胶质瘤中的核心功能和作用机制,探讨其抑制剂治疗胶质瘤的潜能。
Objective DNA-repair pathway genes play an important role in the etiology and progression of breast cancer.BRCA1/2,along withPALB2,CHEK2,andRECQL,is the most commonly mutated genes in hereditary breas
Objective The half-life of Cyclin D1 is about 30 minutes,which is under the tightly control of ubiquitin-proteasomal degradation mechanism during cell cycle progression.