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耐药性细菌大规模流行给治疗细菌感染带来极大挑战，因此迫切寻求新型药物靶标和开发新型抗菌药物。虽然经典遗传学操作是研究细菌生理(包括耐药和致病机制)的主要手段，但是在一些重要的致病菌中，主要的遗传学操作仍旧步骤十分繁琐，耗时耗力。
Genome engineering of human pathogens using CRISPR technology
【摘 要】
：
耐药性细菌大规模流行给治疗细菌感染带来极大挑战，因此迫切寻求新型药物靶标和开发新型抗菌药物。虽然经典遗传学操作是研究细菌生理(包括耐药和致病机制)的主要手段，但是
【机 构】
：
物质科学与技术学院,上海科技大学,上海,200120
【出 处】
：
第十一届全国化学生物学学术会议
【发表日期】
：
2019年11期
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