The immunoregulatory role of corneal epithelium-derived Thrombspondin-1 in dry eye disease

来源 :第六届全国眼科学研究生学术论坛暨眼科细胞及再生生物学世界大会 | 被引量 : 0次 | 上传用户:xiaoyuerlga
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PURPOSE:To investigate the immunoregulatory role of corneal epithelium-derived Thrombospondin-1 (TSP-1) in dry eye disease (DED).METHODS:Acute DED was induced by exposing 6-to 8-week-old female C57BL/6mice to a controlled environment chamber (CEC) for 7 or 14 days.Chronic DED was induced by transferring acute DED mice to a standard vivarium for additional 14days.
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