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Objective: To investigate the association between various risk factors and precancerous lesion of gastric cancer (PLGC) in patients from Jiangsu.This study aimed to assess Toll-like receptor 4 (TLR4) (rs4986790, rs4986791, rs10759932) polymorphisms at risk of precancerous lesion of gastric cancer (PLGC) of Phlegm-Accumulation Stasis in a Chinese Han population.