共刺激分子CD137L在人急性淋巴细胞白血病中的表达及其临床意义

来源 :2012第一届《中华血液学杂志》论坛 | 被引量 : 0次 | 上传用户:ztt399
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
其他文献
Aconitine (AC) is a famous major diterpenoid alkaloid present in the roots of Aconitum species (Ranunculaceae family).Aconitum were widely co-administered with other herbal medicines or prescription d
目的 研究鹰嘴豆芽素A(Biochanin A,BCA)的两种载体的药动学过程.方法 用高效液相法测定血药浓度,计算药动学参数.结果 鹰嘴豆芽素A的固体脂质纳米粒(Biochanin A loaded solid lipid nanoparticles,BCA-SLN)和纳米脂质载体(BiochaninA loaded nanostructured lipid carriers,BCA-NLC)的
目的 考察新藤黄酸固体脂质纳米粒(GNA-SLN)在大鼠体内的药代动力学特征.方法 对大鼠分别腹腔注射新藤黄酸溶液和GNA-SLN,采用HPLC法测定新藤黄酸在大鼠体内的血药浓度,DAS2.1软件拟合计算药动参数.结果 给予等剂量的新藤黄酸溶液和GNA-SLN后,Gmax分别为1.13±0.678和3.466±0.678,AUC(0-t)分别为2.467±0.206和7.683±0.89,t1/2
目的 研究双脱甲氧基姜黄素PLGA微球(CurⅢ-PLGA-MS)大鼠体内药物代谢动力学。方法 采用HPLC法测定尾静脉注射双脱甲氧基姜黄素(CurⅢ)和双脱甲氧基姜黄素PLGA微球(CurⅢ-PLGA-MS)后不同时间血浆、心、肝、脾、肾中CurⅢ的浓度,绘制药-时曲线,计算药物动力学参数。结果 CurⅢ-PLGA-MS在其他组织中分布较少,CurⅢ在肺组织中48 h左右药物浓度最高,且72 h
Strongly acidic group compounds are a class of chemical compounds that have high polarity and large negtive charges.The main members include phosphatic compounds, sulphonic compounds and sulfonic comp
Individual variances usually affect drag metabolism and disposition, and hence result in either ineffectiveness or toxicity of a drug.In addition to genetic polymorphism, the multiple confounding fact
β-lapachone (β-Lap) is an NAD(P)H: quinone oxidoreductase 1 (NQO1) target anti-tumor drug candidate in phase Ⅱ clinical trials.The present study aimed to uncover the metabolic characteristics, enzyme
会议
UDP-Glucucunosyltransferase (UGT) is an important class of phase Ⅱ metabolizing enzymes, playing a pivotal role in detoxifying various substances and in the pathological procedures of some diseases.Th
会议
会议
会议