metabonomics相关论文
目的:运用氢核磁共振(n 1HNMR)技术对遵义地区1岁以下健康留守儿童和1岁以下锌缺乏症留守儿童尿液进行分析,以期为锌缺乏早期......
The abnormality of platelet function plays an important role in the pathogenesis and evolution of blood stasis syndrome ......
Study on Correspondence between Prescription and Syndrome and the Essence of Phlegm and Blood Stasis
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Plasma Metabonomic Analysis with 1H Nuclear Magnetic Resonance Revealing the Relationship of Differe
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Study of Serum Metabonomics and Formula-Pattern Correspondence in Coronary Heart Disease Patients Di
Objectives:To study the characteristics of serum metabonomics in coronary heart disease (CHD) patients diagnosed as phle......
Metabonomics delineates allergic reactions induced by Shuang-huang-lian injection in rats using ultr
Shuang-huang-lian Injection (SHLI) is the first successfully developed drug from traditional Chinese medicine (TCM) powd......
Liver metabonomics study on the protective effect of glycyrrhetinic acid against realgar-induced liv
Glycyrrhetinic acid (GA) is the bioactive ingredient in Giycyrrhizae Radix et Rhizoma.Our previous study has reported th......
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Chronic heat stress (CHS) may trigger systemic biochemical and physiological changes in living organisms.More and more e......
目的 The aims of this study were to characterize the metabolite profiles of triplenegative breast cancer(TNBC)using LC-Q......
Ex vivo 1H NMR spectroscopy reveals systematic alterations in cerebral metabolites as the key pathog
Bilirubin encephalopathy(BE)is a severe neurologic sequelae induced by hyperbilirubinemia in newborns.However,the pathog......
Plasma metabonomics study of the patients with acute anterior uveitis based on ultra-performance liq
Background The identification of the biomarkers of patients with acute anterior uveitis(AAU)may allow for a less invasiv......
Amino acids in plasma metabonomics study on experimental autoimmune uveitis by PITC pre-column deriv
Background: Amino acid disorders are a major group of various forms of aggression and certain nutritional conditions.How......
Analysis of the restorative effect of Bu-zhong-yi-qi-tang in the spleen-qi deficiency rat model usin
Ethnopharmacological relevance: Bu-zhong-yi-qi-tang (BT) is a classical formula for the treatment of spleen-qi descendin......
Liquid chromatography-mass spectrometry based metabonomic investigation into the potential biomarker
Aim: To identify and character the biomarkers in mice suffered the repetitive hypoxia.Methods: A metabonomic method util......
Plasma metabonomics study on the effect and mechanism of Bu-zhong-yi-qi-tang in spleen-deficiency ra
Aim: Bu-zhong-yi-qi-tang (HET) is a traditional Chinese medicine used for the treatment of spleen-deficiency in clinic.H......
Detection of serum and urine metabolic profile changes of CCl4-liver fibrosis in rats at 12 weeks ba
Aim.To investigate serum and urine metabonomics after carbon tetrachloride(CCl4)-induced by the liver fibrosis using gas......
Cardioprotective effects and mechanism of Radix salviae miltiorrhizae and Lignum dalbergiae odorifer
Objective Radix salviae miltiorrhizae (SM) and Lignum dalbergiae odoriferae (DO) are both traditional Chinese medicinal ......
Metabolomics discovery of biomarkers of osteoarthritis in urine of rats and research on the interven
Aim: To observe urine metabolic changes after Xinfeng capsule treatment in knee osteoarthritis (KOA) rats using gas chro......
Serum Metabolic Biomarkers of Liver Failure Patients Caused by Hepatitis B Virus Based upon UPLC-Q-T
Objective: Liver failure is a most emergent clinic complication which leads to the highest mortality around the world, b......
LC-MS based metabonomics investigations into the metabolic profile of acute repetitive hypoxia in mi
OBJECTIVE The metabonomics utilizing LC-ESI-MS and multivariate statistical technique have been applied to investigate t......
Does Electro-Acupuncture Influence the Metabolites-A 1H NMR-Based Metabonomic Study on Healthy Young
Aims: To characterize the alteration metabolites in healthy young men receiving acupuncture at different adjoin acupoint......
GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in d
Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its developmen......
Biomarkers of Primary Dysmenorrhea and Herbal Formula Intervention:An Exploratory Metabonomics Study
Primary dysmenorrhea (PDM), a commonly clinical endocrine disorder affecting young women, is associated with endocrinopa......
LC-MS based metabonomic investigations into the metabolic profile of acute repetitive hypoxia in mic
Objective In this work, the metabonomic methods utilizing LC-ESI-MS and multivariate statistical technique have been app......
Objective: Bladder cancer (BCa) is a common malignancy worldwide and has a high probability of recurrence.Early detectio......
Amino acids in plasma metabonomics study on experimental autoimmune uveitis by PITC precolumn deriva
Background Amino acid disorders are a major group of various forms of aggression and certain nutritional conditions.Howe......
Metabonomic study of Astragaloside Ⅳ in prolonging lifespan of Caenorhabditis elegans based on 1H-NM
Objective:To investigate the anti-aging effects and the changes of endogenous metabolites in Caenorhabditis elegans(C.el......
Metabonomic Strategy to the Evaluation of Chinese Medicine Salvia Miltiorrhiza and Dalbergia Odorife
Aim To investigate the cardioprotective effect of herb pair,extract of Salvia miltiorrhiza and Dalbergia Odorifera (SM-D......
Liquid chromatography-mass spectrometry based metabonomic investigation into the potential biomarker
Aim: To investigate the metabonomics and potential biomarkers for acute repetitive hypoxia.Methods: The metabonomics met......
Backbround:Venlafaxine is a new antidepressant that has a chemical structure and neuropharmacologic profile distinct fro......
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A metabonomics method was developed to investigate the physiological effect of electric induced stress in female Sprague......
1H NMR-based metabonomics study on the antidepressant effect of Xiaoyaosan in plasma of depressed pa
Background: Xiaoyaosan(XYS), a famous Chinese prescription, had been effectively used for the treatment of depression in......
Ethnopharmacological relevance: Xiaoyaosan (XYS) is a famous traditional Chinese medicine prescription with a long histo......
1H-NMR-based metabonomics study on the restorative effect of Bu-zhong-yi-qi-tang in the spleen-qi de
Ethnopharmacological relevance: Bu-zhong-yi-qi-tang (BT) is one of a classical formula for descending of spleen-yang, vi......
NMR-based metabonomic and quantitative real-time PCR in the profiling of metabolic changes in carbon
Carbon tetrachloride (CC14) is commonly used as a model toxicant to induce chronic and acute liver injuries.In this stud......
传统中医药治疗原发性痛经(PD)具有一定特色和优势。本论文以临 床常用经典方剂香附四物汤(XFSWF)为研究对象,在参考中医证候标准的同 ......
Individual variances usually affect drag metabolism and disposition, and hence result in either ineffectiveness or toxic......
Lung cancer is by far the second most common cancer in both man and woman.It is also the leading cause of the cancer dea......
Metabonomic study on kidney tissue of osteoporosis rats and intervention effects of Rhizoma Drynaria
Metabonomics is a quantitative approach to study "the dynamic metabolic response of living systems to pathophysiologica......
Fusion of GC-MS and LC-MS Data for Metabonomic Investigation on the Liver Protection of Herbal Medic
To measure metabolites in a biological system, samples have to be taken and analyzed.There are different instrumental me......
A “prediction-validation” model for the nutritional intervention research of neural tube defects bas
Neural tube defects (NTDs) is a serious birth defect disease which can be effectively prevented through folic acid and v......
Drug discovery is slow and extremely expensive that resulting in low rates of novel agents entering the clinic.One appro......
There is intense interest in the identification of novel biomarkers which improve the diagnosis of Congestive heart fail......
A UPLC/TOF-MS-based metabonomic study on the effect of Siweigantai Soft Capsule on transplanted tumo
Tissue metabonomics is a systemic method to study the biological state and function regulation of organisms by analyzing......
Study of oral cancer based on integrating plasma,urine and saliva metabolic profiles by Gas Chromato
Oral cancer is the eighth most common cancer worldwide with an overall 5-year survival rate of less than 50%.Precise dif......
Bile acids as Novel Indicator of Hepatocellular Carcinoma:Small-Molecule Markers Screening from Bile
The identification of a sensitive and specific serum marker will facilitate the early diagnosis ofhepatocellular carcino......
Metabolomic identification of potential biomarkers for acute graft rejection of renal transplantatio
Acute graft rejection is a major post-transplant complications of renal transplantation, the success of renal transplant......
Rheumatoid arthritis (RA) is a systematic autoimmune disease that causes pain, swelling, stiffness and loss of function ......