Study in the Effect of EZH2 Gene Targeting siRNA on Cell Death in HL-60 Cell Line

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：songfeng816

【摘要】

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【作者】

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xudong Ma luhui Lin

【机构】

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Zhangzhou affiliated hospital of Fujian Medical University

【出处】

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The 35th World Congress of the International Society of Hema

【发表日期】

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2014年5期

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Objective To study small interfering RNA (siRNA) targeting EZH2 gene effect on cell proliferation,apoptosis and histone H3K27 methylation and histone H3 acetylation modulation in HL-60 cells line.Methods (1)Three siRNA segments targeting EZH2 gene were designed and transfected into HL-60 cells by Lipofectamine TM 2000.

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Study in the Effect of EZH2 Gene Targeting siRNA on Cell Death in HL-60 Cell Line

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