Antinuclear Antibody its Significance on Autoimmune Liver Diseases and Clinical Problems

来源 :2011第三届中国北京抗体大会 | 被引量 : 0次 | 上传用户:zhangjunfeng_2009
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  Autoimmune hepatitis (AIH) is a type of chronic hepatitis of unexplained etiology.It has been strongly suggested that autoimmune mechanisms are closely involved in the onset and progression of this disease.Clinically, AIH has been characterized by elevated serum gamma-globulin or IgG levels, positive autoantibodies.Although the IAIHG recommends the indirect immune-fluorescent method with frozen sections of rodent liver, kidney and stomach to check for autoantibodies involved in AIH, this method is now used only at limited clinical facilities and a larger number of facilities adopt ELISA or a method using established cell lines.
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