HLA and Cancer: From Geno-susceptibility to Clinical Use

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  The human leucocyte antigen system (HLA) is a large genomic region or gene family that encodes MHC molecules.MHC molecules play an important role in the immune system and cancer development.The most polymorphic genes of HLA, with more than 6000 alleles, are not only population specific and disease specific, but also clustered in the functional peptide binding domains.
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