Gene therapy and oncolytic viral therapy are studied separately and their international conferences are also held separately.We combined them together to initiate the strategy "Cancer Targeting GeneViro-Therapy, CTGVT" which is constructed by inserting a good antitumor gene into an oncolytic virus (OV).Therefore, CTGVT is actual an OV-gene therapy and has higher antitumor effect than either gene therapy alone or oncolytic viral therapy alone.This is because that the oncolytic virus can target and replicate several hundred folds in cancer cell and the inserted antitumor gene also increased several hundred folds in accompany.