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5. Exploiting human γδ T-cells for tumor therapy

Exploiting human γδ T-cells for tumor therapy

来源 :第四届中德免疫学研讨会 | 被引量 : 0次 | 上传用户：darkblueangel

【摘 要】

：

γδ T-cells exert potent cytotoxicity against many solid tumors and haematological malignancies.In the case of human Vγ9Vδ2 T-cells, it is the CD277/BTN3-dep

【作 者】

：

Dieter Kabelitz 

【机 构】

：

InstituteofImmunology,UniversityofKiel,Kiel,Germany

【出 处】

：

第四届中德免疫学研讨会

【发表日期】

：

2015年11期

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论文部分内容阅读

γδ T-cells exert potent cytotoxicity against many solid tumors and haematological malignancies.In the case of human Vγ9Vδ2 T-cells, it is the CD277/BTN3-dependent but MHC-independent recognition of isoprenoid metabolites overproduced in transformed cells that endows γδ T-cells with the tumor-killing capacity.

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