Study molecular mechanisms of CIRP involved in protective effect of hippocampal neurons under mild h

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:officerkaka
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Objective To explore that CIRP(Cold-inducible RNA-binding protein)could inhibit neuronal apoptosis by adjusting the relevant redox level,and then inhibited the formation of oxygen free radicals whether or not.
其他文献
Background: Recent researches indicate that neuroinflammation has an important role in the pathophysiology of depression.Our previous study discovered that the NLRP3 inflammasome,a multi-protein compl
会议
Background: Glucocorticoids(GCs)are a class of steroid hormones that regulate multiple aspects of glucose homeostasis.In skeletal muscle,it is well established that prolonged GC excess inhibits glucos
会议
Objective: Hypoxic preconditioning(HPC)has been shown to be protective against injuries induced by hypoxia exposure and effective in improving tolerance or performance at high altitude.Previous studie
Depression disorder is a common,chronic and life debilitating mental illness and its mechanism remains unclear.Our previous research indicated that high-mobility group box 1(HMGB1)protein was actively
Background: The increasing prevalence of overweight and obesity is a critical public health problem for women.The negative effect of stress on memory and cognitive functions has been widely explored f
Medullary airway vagal preganglionic neurons(AVPNs)within the external formation of nucleus ambiguus are particularly important in the neural control of airway smooth muscle.Corticotrophin-releasing h
As the entry point of information into the hippocampus,the hippocampal dentate gyrus(DG)encodes and processes new information and plays an essential role in learning and memory.Stress is ubiquitous in
Objective: The antioxidant and antiapoptotic effect of lycium barbarum polysaccharide(LBP)on on aortic endothelial cells injury induced by oxidative stress were explored,then the exploration provides
O-GlcNAcylation,a dynamic process that is catalyzed by O-GlcNAc transferase(OGT)and O-GlcNAcase(OGA),represents a signal transduction pathway that plays critical roles in a variety of cellular process
Objective: Excessive accumulation of free radicals(ROS)is an important mechanism of the exercise-induced skeletal muscle fatigue.The increase in ROS generation cause oxidative stress and overload intr
会议