无症状脑转移、表皮生长因子受体突变阳性的非小细胞肺癌患者的治疗方案选择:脑部放疗的最佳时机?

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户：doujiazhi

【摘要】

：

目的:脑转移为非小细胞肺癌(NSCLC)患者的常见并发症,自然病程通常为4-11周.全脑放疗(WBRT)将此类患者的生存期延长至3-6个月,但有效率仅为25-30％.表皮生长因子受体(EGFG)酪氨酸激酶抑制剂(TKI)的应用,进一步延长了EGFR突变阳性脑转移患者的生存期.然而高达11-44％的脑转移灶对TKI抗拒.本试验通过系统性回顾EGFR突变阳性、无症状脑转移的NSCLC患者的临床资料,分

【作者】

：

刘慧刘松然邱波陈立坤王芳梁颖蔡培强张力陈昭琳刘孟忠

【机构】

：

510080 中山大学肿瘤防治中心放疗科 510080 中山大学肿瘤防治中心化疗科

【出处】

：

第十七届全国临床肿瘤学大会暨2014年CSCO学术年会

【发表日期】

：

2014年11期

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无症状脑转移、表皮生长因子受体突变阳性的非小细胞肺癌患者的治疗方案选择:脑部放疗的最佳时机?

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