Single-nucleotide polymorphisms in VTI1A gene contribute to the susceptibility to non-small cell lun

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户：jeaceinter

【摘要】

：

【作者】

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Wen-mei Su Zhi-hong Chen Xu-chao Zhang Zhi Xie Jian Su Shi-liang Chen Yi-long Wu

【机构】

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510080 广东省人民医院广东省医学科学院广东省肺癌研究所

【出处】

：

第十七届全国临床肿瘤学大会暨2014年CSCO学术年会

【发表日期】

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2014年11期

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Objective: This study was to evaluate the association between single-nucleotide polymorphisms (SNP) in VTI1A gene and the susceptibility to lung cancer in never-smoking Chinese patients, and investigate the relationship between VTI1A SNP and expression of adiponectin receptor.Method: 887 subjects were enrolled in this study from Guangdong General Hospital.The genotypes of VTI1A (rs7086803) were determined in 746 lung cancer patients and 141 normal subjects by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).Overall survival (OS) was evaluated by Kaplan-Meier test and Cox model.

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Single-nucleotide polymorphisms in VTI1A gene contribute to the susceptibility to non-small cell lun

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