【摘 要】
:
Outline · Factors Influencing Solid-State Reactivity · Drug-Excipient Reactions: RGD Peptide · Moisture-Mediated Reaction Partitioning:CancidasTM · Concluding Remarks Factors Influencing Solid-State D
【机 构】
:
Vice President-Technical Development Biogen Idec
【出 处】
:
2013 International Symposium on Pharmaceutical Solid-State R
论文部分内容阅读
Outline · Factors Influencing Solid-State Reactivity · Drug-Excipient Reactions: RGD Peptide · Moisture-Mediated Reaction Partitioning:CancidasTM · Concluding Remarks Factors Influencing Solid-State Degradation of Pharmaceuticals · Intrinsic Reactivity-Ester hydrolysis-Sulfur oxidation · Molecular Mobility-Crystalline vs amorphous · Availability of Reactant Molecules-Water-Oxygen-Others
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