Nature provides high-efficiency biological catalysts(e.g.protein enzymes or ribozymes)to catalyze essential chemical reactions to maintain the life functions.Bioinspired artificial enzymes on the molecular or nanoscale level have been focused for various transformations,such as kinetic resolution or synthesis of functional materials.The development of effective strategies to tune the catalytic behaviors flexibly has been attracting much attention.The programmability and designability of nucleic acid self-assembly can open a new avenue to the design,construction and modulation of the artificial catalytic systems.