【摘 要】
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目的 To reveal the relationship between the cytokines and OSAS developed asthma, and evaluate their clinical effect.方法 Data acquired from Polysomnography (PSG) were used to diagnosis Obstructive sleep a
【机 构】
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the Second Department of Respiratory Internal Medicine,Xi'an Children Hospital
【出 处】
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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议
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目的 To reveal the relationship between the cytokines and OSAS developed asthma, and evaluate their clinical effect.方法 Data acquired from Polysomnography (PSG) were used to diagnosis Obstructive sleep apnea syndrome (OSAS) according their Pittsburgh Sleep Quality Index (PSQI).The serum samples of OSAS children with and without asthma were collected by double blind method.The quantities of cytokine were analyzed by cytokine microarray.The clinical data of the patients were analyzed, and the confounding factors were excluded.The means with statistically significance, which differences was great than 10 times, were adopt.According to significant sequence, the preceding 5 factors were selected.OSAS in pediatric patients without asthma were followed up to observe the prevalence of asthma in high-level expression with the 5 factors at least 2 years.结果 These study included 716 cases between May, 2013 and December, 2015.PON2, VEGF, IL-11, TNF-γ,MCP2 were selected as an early serological marker for Asthma in children with OSAS.Their compliance rates were greater than 73.1％.结论 There is a certain correlation between OSAS and asthma, which can provide evidence for early intervention through the detection of related cytokines.
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