CONSTITUTIVE STAT6 ACTIVATION IN PRIMARY EFFUSION LYMPHOMA

来源 :17th International Workshop on Kaposi’s Sarcoma Associated H | 被引量 : 0次 | 上传用户：xuyi50488

【摘要】

：

Activation of the Janus Kinase (JAK) / signal transducer and activator of transcription (STAT) signaling pathway has been associated with a range of human malig

【作者】

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Caixia Zhu Chong Wang Xiaohui Mo Qiliang Cai

【机构】

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MOE&MOHKeyLaboratoryofMedicalMolecularVirology,SchoolofBasicMedicine,ShanghaiMedicalCollege,FudanUni

【出处】

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17th International Workshop on Kaposi’s Sarcoma Associated H

【发表日期】

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2014年7期

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Activation of the Janus Kinase (JAK) / signal transducer and activator of transcription (STAT) signaling pathway has been associated with a range of human malignancies.Primary effusion lymphoma (PEL), a cancerous proliferation of lymphocytic B-cells, is caused by the Kaposis sarcoma-associated herpesvirus (KSHV).Our previous study showed that constitutively phosphorylation of STAT6 on tyrosine 641 (pSTAT6) in both PEL cell lines BC3 and BCBL1.

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CONSTITUTIVE STAT6 ACTIVATION IN PRIMARY EFFUSION LYMPHOMA

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