Background Hypoxic pulmonary vasoconstriction (HPV) was driven by the intrinsic response to hypoxia of pulmonary arterial smooth muscle.Hypoxia resulted in pulmonary hypertension and vascular remodeli
BACKGROUND Emphysematous change on computed tomography (CT) during the stable phase of chronic obstructive pulmonary disease (COPD) is reported to correlate with prognosis of COPD.Acute exacerbation o
Background Sarcoidosis pleural disease is uncommon.Most published cases are not pathologically proven.Medical thoracoscopy permits internists detecting pleural cavity directly and increases the diagno
Objective To deternine whether the mannose receptor(MR) is involved in asthmatic pathophysiological mechanism and regulates the endocytosis activity of alveolar macrophages(AMs).
Background Airway remodeling is a repair process occurring after airway injury and involves a wide array of pathophysiologic features, resulting in increased airway hyperres-ponsiveness in asthma.Thym
Background Although viruses are thought to cause epithelial cell injury, it remains unclear whether virus promote epithelial-mesenchymal transition (EMT).In this study, we established Epstein-Barr vir
实时超声弹性成像技术是利用组织在外力作用下产生的形变大小对组织软硬度的评估,该技术已逐步应用于浅表淋巴结良恶性的鉴别.目的 探讨经支气管镜实时超声弹性成像在判断肺门纵膈淋巴结良恶性的诊断价值.
目的 总结支气管镜检查并发出血的防治措施.方法 回顾性分析2001年1月～2012年7月昆明市第一人民医院呼吸2科行支气管镜检查的2079例患者并发出血的情况.结果 行支气管镜检查的2079例患者中并发出血者51例(2.45％),其中少量出血31例(1.49％)、中量出血14例(0.67％),大量出血6例(0.29％),无死亡病例.并发出血的原发病主要是肺癌,出血主要由对支气管腔内病灶刷检、活检及
Background People pay attention on the relationship between vitamin D "pathway" and lung cancer mainly because of the results from epidemiological studies.Some research support VDR has effect in lung
Objectives: Phosphatidylinositol-3 kinase (PI3K)/Akt signaling represents a key survival mechanism in cancer cells and has emerged as an attractive cancer therapeutic target.NVP-BKM120 (BKM120) is a n