【摘 要】
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The 5cap structures of eukaryotic mRNAs are important for RNA stability and protein translation.Many viruses that replicate in the cytoplasm of eukaryotes have evolved 2-O-methyltransferases (2-O-MTas
【机 构】
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State Key Laboratory of Virology,College of Life Sciences,Wuhan University,Wuhan,China
【出 处】
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第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会
论文部分内容阅读
The 5cap structures of eukaryotic mRNAs are important for RNA stability and protein translation.Many viruses that replicate in the cytoplasm of eukaryotes have evolved 2-O-methyltransferases (2-O-MTase) to autonomously modify their mRNAs and carry a cap-1 structure (m7GpppNm) at the 5end,thereby facilitating viral replication and escaping innate immune recognition in host cells.
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