【摘 要】
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Introduction: Mucosal infiltration of macrophages with compromised phagocytic activity has been implicated in local inflammation and damage of intestinal barrier,contributing to HIV immunopathogenesis
【机 构】
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ABSL-3 Laboratory at the Center for Animal Experiment,Wuhan University School of Basic Medical Scien
【出 处】
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第十一届全国病毒学学术研讨会暨第六届武汉现代病毒学国际研讨会
论文部分内容阅读
Introduction: Mucosal infiltration of macrophages with compromised phagocytic activity has been implicated in local inflammation and damage of intestinal barrier,contributing to HIV immunopathogenesis.However,recent data on rectum macrophages in HIV infection are sparse.Objectives: In the present study,we investigated the effect of topical use of(-)-Epigallocateehin gallate(EGCG),a bioaetive component from green tea,on the accumulation of immune cells at the rectal mucosa in the macaque model upon SHIVSF162p3n challenge.
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