A FOLDING SWITCH-LIKE DELIVERY SYSTEM USING BIODEGRADABLE PCL-COATED HOLLOW MESOPOROUS SILICA NANOPA

来源 :The 6th International Symposium on Polymer Chemistry(2014年第六 | 被引量 : 0次 | 上传用户:ywanywhere
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A novel folding switch-like hollow mesoporous silica nanoparticles(HMSN)-based delivery system is reported.In this system,PCL(polycaprolactone) is grafted on the surface of HMSN as a cap.When Dispersed in THF,the PCL unfold the molecule chain due to the good solvent of PCL.While PCL switch back to folded chain to cap the pore again in H2O.
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