Mechanism of Telomeric DNA Extension by Telomerase

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户:detectivexiat
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  Telomerase is a reverse transcriptase consisting of RNA and protein subunits.Its main function is extension of the single-stranded ends of telomeric DNA, thereby preventing telomere erosion in dividing cells.In cancer cells and cancer stem cells this activity of telomere as enables their replicative immortality and consequent tumor growth.
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