A novel PADI4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute prom

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:scnbyfy
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  Aims: The hematologic malignancy acute promyelocytic leukemia (APL) exhibits a failure of myeloid differentiation.Most patients with APL can be induced to complete remission by all-trans retinoic acid (ATRA) or arsenic trioxide treatment through presumed degradation of the PML-RARα fusion protein.
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