Oridonin相关论文
器官移植是治疗终末期器官疾病的最有效的治疗措施。器官移植可以明显改善患者生活质量,提高生存率,但是移植术后的排斥反应仍是阻......
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Oridonin induces apoptosis in gastric cancer through Apaf-1, cytochrome c and caspase-3 signaling pa
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Cytotoxicity and Cellular Kinetics of Oridonin-Loaded Cholesterol Formate-Graft Chitosan Copolymer N
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Oridonin inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the MAPKs
Objective.Oridonin, an active diterpenoid compound from Rabdosia rubescens,has effects of anti-tumor,treating multiple m......
Aims: Combined application of different kinds of drugs is an important research direction to cure tumor or leukemia,whic......
Studying on the medicinal value and the SAR of natural compounds and their derivatives is one of the most important meth......
It has been reported that Oridonin (ORI) can inhibit proliferation and induce apotosis in various cancer cell lines.Howe......
Oridonin inhibits invasion and metastasis of human breast cancer cells via suppression of MMPs and i
AIM Oridonin, a natural tetracycline diterpenoid isolated from Chinese herb Rabdosia rubescens, has been reported to be ......
Oridonin(1)is a complex ent-kaurane diterpenoid isolated from Isodon rubescens which displays remarkable antitumor activ......
Combined oridonin,a natural and safe kaurene diterpenoid isolated from Rabdosia rubescens,and cetuximab,an anti-EGFR mon......
The method of determination of oridonin in the crude drugs by HPLC with a new phenylalanine substituted calyx [4] arene ......
Effects and mechanism of oridonin on pulmonary hypertension induced by chronic hypoxia-hypercapnia i
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Combination of Oridonin and Cetuximab Synergistically Exerts Apoptosis and G2M Arrest on Laryngeal S
Epidermal growth factor receptor(EGFR),a transmembrane glycoprotein,is expressed at high levels in a large proportio......
Currently,dendritic cell-specific transmembrane protein (DC-STAMP),a multipass transmembrane protein,is considered as th......
为研究二萜类化合物冬凌草甲素（Oridonin）对拟南芥的化感潜能作用,本研究以Oridonin为供体,以哥伦比亚野生型拟南芥WT和三个拟南芥磷......
Static and dynamic studies of adsorption by four macroporous resins to enrich oridonin from Rabdosia
Oridonin,one of the active ingredients in Rabdosia rubescens(R.rubescens),has been reported to induce cell apoptosis and......
从瘿花香茶菜Rabdosia rosthornii(Diels)Hara的叶和茎中分离出三种二萜类化合物。其中两种为已知化合物ponicidin和oridonin。另......
PC SPES是一种饮食补充剂,由一种北美植物(锯齿棕)和7种中草药(菊花、灵芝、甘草、菘蓝、三七、碎米桠和黄芩)的提取物组成。由于......
目的 考察冬凌草甲素片口服给药对醋酸诱导的小鼠溃疡性结肠炎的治疗作用.方法 醋酸诱导的溃疡性结肠炎小鼠分别给予不同剂量的冬......
目的建立高效液相色谱法测定毛叶香茶菜中迷迭香酸和冬凌草甲素含量的方法。方法采用Kromasil C18色谱柱(250 mm×4.6 mm,5μm),以......
目的介绍冬凌草甲素靶向制剂的研究现状。方法综述近年来国内外相关研究,介绍靶向制剂靶向原理和特性、药动药效学研究进展,并对其......
Aim:To investigate the apoptosis-inducing effect of oridonin,a diterpenoid isolated from Rabdosia rubescens,in the human......
,Oridonin induces apoptosis of HeLa cells via altering expres sion of Bcl-2/Bax and activating caspa
AIM: To study the mechanisms by which oridonin inhibited HeLa cell growth in vitro. METHODS: Viability of oridonin-induc......
Aim: To study the intravenous and oral pharmacokinetic behavior of oridonin and its extent of absolute oral bioavailabil......
,P53-mediated cell cycle arrest and apoptosis through a caspase-3-independent, but caspase-9-depende
Aim: To study the caspase-3-independent mechanisms in oridonin-induced MCF-7 human breast cancer cell apoptosis in vitro......
,Reactive oxygen species contribute to oridonininduced apoptosis and autophagy in human cervical car
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,Oridonin induces apoptosis and autophagy in murine fibrosarcoma L929 cells partly via NO-ERK-p53 po
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Collaboration of c-KIT mutations with AML1-ETO (AE) has been demonstrated to induce t(8;21) acute myeloid leukemia (AML)......
,Inhalable oridonin-loaded poly(lactic-co-glycolic) acid large porous microparticles for in situ tre
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Oridonin, a diterpenoid isolated from Rabdo-sia rubescens (Hemsl.) Hara, has been proved to possess remarkable anticance......
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,Downregulation of IncRNA AFAP1-AS1 by oridonin inhibits the epithelial-to-mesenchymal transition an
Recent studies have demonstrated that the expression of the long non-coding RNA (IncRNA) AFAP1-AS1 in pancreatic cancer ......
目的研究冬凌草甲素(Oridonin,ORI)对膀胱癌T24细胞的作用及机制。方法MTT法检测ORI对T24细胞的生长抑制作用;光学显微镜和Hoechst......
Effects and mechanism of oridonin on pulmonary hypertension induced by chronic hypoxia-hypercapnia i
Background Pulmonary arterial hypertension (PAH) is characterized by suppressing apoptosis and enhancing cell proliferat......
OBJECTIVE To study the inhibitory effect of oridonin on the growth of cancer cells.METHODS Fifteen human cancer cell lin......
目的采用HPLC法测定冬凌草药材及片剂中的冬凌草甲素。方法用Hypersil C18(250mm×4.6mm,5μm)色谱柱,甲醇-水(50∶50)为流动相,流......
目的观察冬凌草甲素(Ori)对胃癌细胞株SGC7901/ADR多药耐药性的逆转及其作用机制。方法用MTT法检测Ori的非细胞毒浓度及对SGC7901/......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨冬凌草甲素对急性单核细胞白血病THP-1细胞的诱导凋亡作用及其作用机制.方法 以不同浓度的冬凌草甲素(16～56 μmol/L)作用......
冬凌草甲素(oridonin,ORI)是从中草药冬凌草中提取出来的一种具有抗肿瘤活性的二萜类化合物.ORI作用于肿瘤细胞后,主要经线粒体途......
目的 探讨冬凌草甲素体外诱导胃癌SGC-7901细胞凋亡和细胞周期阻滞的作用及其机制.方法 10～80 μmol/L冬凌草甲素分别处理SGC-7901......
目的 观察冬凌草甲素(ORI)诱导前列腺癌PC-3细胞自噬,探讨ORI抗前列腺癌的可能机制.方法 实验应用MTT检测细胞存活率、扫描电镜和......
目的 探讨冬凌草甲素是否具有抑制PC-3细胞转移的能力及其分子机制.方法 用不同浓度的冬凌草甲素作用于PC-3细胞,用体外驱化运动实......
目的观察冬凌草甲素对人宫颈癌HeLa细胞增殖、凋亡、迁移、侵袭及Wnt/β-连环蛋白(β-catenin)信号通路的影响。方法体外培养HeLa......
目的研究冬凌草甲素(Ori)减轻大鼠脑外伤(TBI)的作用及机制。方法36只雄性SD大鼠按随机数字表法分为对照组、TBI 3 d组和TBI 3 d+O......
目的探讨冬凌草甲素对神经胶质瘤U87细胞增殖、迁移和凋亡影响及其作用机制是否涉及抑制YAP-c-Myc信号通路。方法采用MTT法检测冬......
目的建立测定冬凌草糖浆的冬凌草甲素含量的高效液相色谱法。方法采用Diamonsil C18色谱柱（250 mm×4.6 mm,5μm）,以甲醇-水（50∶......
