2,3-Dihydroquinazoline-4(1H)-one derivatives belong to an important class of nitrogen heterocycles that attracted much attention because these quinazolinone scaffolds as core unit for a wide spectrum
An efficient solvent-depended regioselective [3+2]-cycloaddition/iodocyclization cascade reaction of alkyne-tethered chalcones/cinnamates and TosMIC have been developed.
Lewis acid B(C6F5)3 catalyzed the Diels-Alder reactions of multi-substituted open-chain dienes and α,β-enals to afford the desired products with high exo-selectivities was reported.
A palladium-catalyzed intermolecular alkylation of enamides with α-bromo carbonyls was developed.Under the mild reaction conditions,various cyclic and acyclic enamides could react well with α-bromo ca
The carboxylic acids are readily available,more stable compared with enal and the functionalized aldehydes including α-aryloxy acetal aldehydes and halogenated aldehydes employed previously in NHC-cat
Carboxylic acids y are less liable to enolize than ketone and activated esters,which may avoid the occurrence of the side reaction including aldol condensation,Michael addition and Claisen condensatio