It is still a challenge to explore the carboydrate-protein interactions in living cell as the weak binding affinity of protein-carbohydrate interaction.As divalent oligosaccharide probes can efficient
2,4-Dinitrobenzenesulfonyl(DNBS) has been widely used for the design of small fluorescent probes for biothiols due to its high reactivity.However,most DNBS-based fluorescent probes exhibit "off–on" fl
Qualitative and quantitative analysis of N-glycans by matrix assisted laser desorption/ionization mass spectrometry(MALDI-MS) is hampered mainly by the low ionization efficiency of analytes and their
Metalloporphynns are active sites in metalloproteins and synthetic catalysts.[1]We recently used iron protoporphyrin Ⅸ(FePPⅨ) as an intercalating probe for long-range electrochemical electron transfer
The three biological thiols(Cys,Hcy and GSH) can be effectively distinguished by fluorescent probes supported by their pKa values of sulfydryl induced nucleophilic reaction activities differences of-S
Protein-membrane interactions plays important roles in topology of protein inserted in the membrane,regulation of protein activity,protein aggregation and signal transduction.