【摘 要】
:
INTRODUCTION: Macrophages can be classified phenotypically into two main groups,namely classically activated macrophages (M1) and alternatively activated macrophages (M2).M2 macrophages can be polariz
【机 构】
:
Laboratorary of Immunology for Environment and Health,Shandong Analysis and Test Center,Shandong Aca
【出 处】
:
第八届全国医学生物化学与分子生物学、第五届全国临床应用生物化学与分子生物学、2013华东六省一市生物化学与分子生物学联合
论文部分内容阅读
INTRODUCTION: Macrophages can be classified phenotypically into two main groups,namely classically activated macrophages (M1) and alternatively activated macrophages (M2).M2 macrophages can be polarized further with cytokines into M2a (after exposure to IL4 or IL-13) and M2c (IL-10 or TGFbeta).
其他文献
RAS proteins are small GTPases that act as molecular switches,transducing signals from many activated receptors that regulate cell proliferation,survival,and differentiation.
Recently, a novel class of transcripts, long noncoding RNAs (lncRNAs),is being identified at a rapid pace.These RNAs act critical roles in diverse biological processes including tumorigenesis.
Digital PCR has recently become recognized as a powerful tool for analyzing somatic mutations in cancers.
As an endogenous anti-injury sulphonic acid with simple chemical structure, taurine (Tau) is well-known for its multiple physiological functions.
类风湿关节炎(RA)是一种主要累及关节的慢性自身免疫病,致残率高,严重影响病人的生活质量和预期寿命,一直是世界研究热点.在RA发病机制中,促炎细胞因子TNFα和自身反应性T淋巴细胞发挥了关键作用,高浓度TNFα和T细胞与软骨和骨破坏等密切相关.
Angiogenin is a 14kDa protein that is significantly upregulated in many types of human cancers.It stimulates both tumor angiogenesis and cancer cell proliferation by promoting ribosomal RNA (rRNA) tra
随着稀土在农业、工业、畜牧业和现代医药学等领域中的广泛应用,它将不可避免的进入环境,并通过生态系统的食物链等途径进入生物体.因此,有关稀土对生物体的影响机制等问题一直是人们关注的焦点.本课题的研究目的是探讨稀土离子引起DNA损伤的机理.
Aims: Blood stasis syndrome was wildly accepted as the most common subclass of coronary artery disease (myocardial ischemia).
目的:筛选食管鳞状细胞癌(ESCC)患者血清中显著升高而在术后明显降低的血清miRNA,评价其对ESCC患者的临床应用价值.方法:收集未经任何治疗的63例ESCC患者术前和对应的术后两周的血清样本,并对部分患者跟踪随访,以63例年龄、性别匹配的非癌正常人血清作对照.
Application of novel and effective biomarkers in the practice for treating head and neck squamous cell carcinoma (HNSCC) is a so important and urgent work.