【摘 要】
：
LHRH receptors represent a nearly ideal target for personalized medicine approach.LHRH receptors are according to literature expressed in human cancer tissues (e.g.breast cancer > 60 % and endometrial
【机 构】
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Aeterna Zentaris Inc.Canada
论文部分内容阅读
LHRH receptors represent a nearly ideal target for personalized medicine approach.LHRH receptors are according to literature expressed in human cancer tissues (e.g.breast cancer > 60 % and endometrial and ovarian cancer approximately 80 %).Presence has also been demonstrated in prostate and bladder cancer.The receptors are also detected in tumor metastasis.So far they have only been determined also in reproductive tissue and the pituitary.Therefore, the LHRH receptor allows specific targeting of cytotoxics to tumor cells expressing the receptor.LHRH antagonist can be used for targeting of cytotoxic and a companion diagnostic can be developed.
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