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  5. Coupling of Junctophilin2 to RyR2 in mouse myocardium

Coupling of Junctophilin2 to RyR2 in mouse myocardium

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：lrg123
【摘 要】
：
Introduction: Junctophilins(JPs)are membrane-binding proteins within the junctional membrane complexs,which can bind both the plasma membrane and endoplasmic/sarcoplasmic reticulum(ER/SR)membrane.Ryan
【作 者】
：
Fan hongkun Luo tianxia Zhang panpan Rui dandan Ma xiaofang Yang chun Zhang qian 
【机 构】
：
Department of Physiology,School of basic Medicine of Zhengzhou University
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
JP2 RyR2 protein-protein interaction calcium transients 
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　　Introduction: Junctophilins(JPs)are membrane-binding proteins within the junctional membrane complexs,which can bind both the plasma membrane and endoplasmic/sarcoplasmic reticulum(ER/SR)membrane.Ryanodine receptor 2(RyR2)is an intracellular Ca2+release channel existing in the SR of mammalian cells.In the present study we documented the interaction of JP2 with RyR2 in the cardiac muscle.
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