Design and synthesis of novel dual inhibitors of NF-KB and Akt activation against lung adenocarcinom

来源 :22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) | 被引量 : 0次 | 上传用户：rdview

【摘要】

：

Objective: The C-2 arylidene analogs ofpentacyclic triterpenoid Lantadene A (1) and B (2) were synthesized as dual inhibitors of NF-iB and Akt.The compounds were further evaluated for in vivo anticanc

【作者】

：

Manu Sharma Navin Tailor Suthar Kumar

【机构】

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Department of Pharmaceutical Chemistry,Jaypee University of Information Technology,Waknaghat,Solan I

【出处】

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22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)

【发表日期】

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2013年7期

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