冠心病患者中循环PCSK9与血小板参数的相关性研究

来源 :2014年第十二届全国脂质与脂蛋白学术会议 | 被引量 : 0次 | 上传用户:kkk0089
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目的:探讨人蛋白原转化酶枯草杆菌蛋白酶9 (proprotein convertase subtilisin/kexin type 9,PCSK9)在冠心病患者中与血小板各参数的相关性.为评价PCSK9与血小板在冠心病发生发展是否存在相互关系提供一定的理论依据.方法:2012年10月~2014年4月,连续收录我院血脂病房收治的接受冠状动脉造影证实并且尚未进行降脂药治疗的稳定型冠心病患者330例.采集患者病史及临床特征,所有研究对象均进行血常规、生化等常规检查提供血小板参数及血脂等数据.血浆PCSK9检测采用酶联免疫吸附法测定.
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