Actinomycetes have been well known for their abitity and potential to produce useful secondary metabolites for the use in the pharmaceutical,food or agriculture industries One of the most prominent bioactive producer is the Streptomycetes spp.In this study,soil samples were collected from several areas in Malaysia.A total of 320 isolates of Streptomycetus spp.were isolated from the soil samples collected using soil suspension method [1,2].