Adrenomedullin and Tumor Angiogenesis: From Discovery towards Translational Research

来源 :2014第七届世界癌症大会 | 被引量 : 0次 | 上传用户:C263185
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Adrenomedullin (AM) is a multifunctional peptide hormone involved in cellular proliferation, survival and angiogenesis.AM expression isup-regulated by hypoxia (a typical feature of solid tumours) and a potential role as a regulator of tumour progression has been proposed based on studies in vitro and in animal models.
其他文献
The hormesis phenomena or J-shaped dose responses have been accepted as common phenomena regardless of the involved biological model, endpoint measured and chemical class/physical stressor.This presen
会议
The entity of circulating tumor cells becomes more and more important and attracts the scientific interest due to their involvement in tumor metastases.The new entity of tumor initiating cells is also
会议
This paper introduces the authors personal experiences in the treatment of cancer in Taiwan applying an integrated traditional Chinese medicine (TCM) and Western medicine approach.If Western medicine
会议
This is a case of a 38 year old female suffering acute lyrnphoblastic leukemia treated with both bone marrow transplantation and Chinese medicine.In January of 2006 she underwent bone marrow transplan
会议
Cancer stem cells (CSCs) are thought to be responsible for the high recurrence and chemoresistance of pancreatic cancer.Deregulated autophagy may involve in cancer progression.However, the role of aut
会议
Background: Modulated electro-hyperthermia (oncothermia, OTM) is a non-invasive technique for targeted tumor treatment [1].The strongly impedance coupled modulated radiofrequency selectively enriches
Cell-penetrating peptides provide a unique platform to create a new generation of cancer therapeutics with enhanced efficacy and diminished toxicity.In our previous study, enhanced expression of tolll
会议
The F-box and leucine-rich repeat protein 10 (Fbx110, also known as Jhdm1b or Kdm2b) has many roles concerned with the regulation of proliferation, growth, differentiation, senescence and apoptosis in
会议
RSK2 is a member of Ribosomal S6 kinases family, which is downstream of the mitogen-regulated Ras/ERK-MAP kinase signaling pathway.We found that RSK2 phosphorylates caspase-8 and Thr263 was identified
会议
Recent publications showed that aberrant tncRNA expression plays an important role in hepatocarcinogenesis.Potentially, lncRNAs can become diagnostic and prognostic markers as well as the therapy targ
会议