Wnt signaling: a new target for treating bone cancer pain

来源 :The 6th Asian Pain Symposium, APS 2015(第六届亚洲疼痛研讨会) | 被引量 : 0次 | 上传用户：DJ_BOY

【摘要】

：

　　Bone cancer pain is one of the most common symptoms presented by patients with primary bone sarcomas and predominantly occurs as distant metastases of non-b

【作者】

：

Xue-JunSong;

【机构】

：

Neuroscience Research Institute and Center for Pain Medicine, Peking University,Beijing, China

【出处】

：

The 6th Asian Pain Symposium, APS 2015(第六届亚洲疼痛研讨会)

【发表日期】

：

2015年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Bone cancer pain is one of the most common symptoms presented by patients with primary bone sarcomas and predominantly occurs as distant metastases of non-bone primary tumors, notably those in breast, prostate, and lung.Tumor cells act to cause pain in many ways.

其他文献

REDOX AND ZINC-DEPENDENT MODULATION OF T-TYPE CA2+ CHANNELS IN SENSORY NEURONS CONTRIBUTES TO PERIPH

　　Neuropeptide substance P (SP) is both produced and released by a subset of peripheral sensory neurons that respond to tissue damage (nociceptors);these neur

会议

Mechanisms underlying the peripheral sensitization of bone cancer pain

　　Bone cancer pain resulting from primary tumors or tumors that metastasize to bone is one of the most severe and intractable types of cancer pain, which redu

会议

Epigenetic regulation of P2X3Rs in diabetic neuropathic pain

　　Painful diabetic neuropathy is a common complication of diabetes by mechanisms that as yet are incompletely defined.The aim of the present study was to expl

会议

How can pain sensation and affection be modulated?--One answer lies in prefrontal cortex

　　The medial prefrontal cortex (mPFC) is implicated in processing sensory-discriminative and affective pain.Nonetheless, the underlying mechanisms are poorly

会议

Bone cancer pain in rodents and spinal neuroinflammation-related factors

　　Objective Cancer pain, especially bone cancer pain, affects the life quality of cancer patients, and current treatments for this pain are limited.The neuroi

会议

Ozone interventional composite therapy for intractable PHN of irritable nociceptor type, the result

　　Objective Neuropathic pain (NP) is a complex, chronic painful disease and most of them are still an intractable painful disease of worldwide even at present

会议

Toll-Like Receptor-4/p38 Mitogen-Activated Protein Kinase (MAPK) Signaling in the Dorsal Horn Partia

　　Background: Our previous research suggested that the microglial P2X4 purinoceptor (P2X4R) is involved in the activation of toll-like receptor-4 (TLR4) and t

会议

Differential roles of parabrachial nucleus in pain and itch

　　Spinal cord projection neurons mainly target the parabrachial nucleus, which could be important in pain and itch signal processing.However, the synaptic pro

会议

New mechanisms of metastatic bone cancer pain: cancer tissue-derived ENDOGENOUS formaldehyde activat

　　In recent years, our serial investigations focused on the role of cancer cells-derived endogenous formaldehyde in bone cancer pain.We found that cancer cell

会议

Neuropathic pain: Sensory fiber injury or motor fiber injury?

　　Peripheral nerve injury often induces chronic neuropathic pain.While peripheral nerve is consisted of sensory fibers and motor fibers, injury to which type

会议

Wnt signaling: a new target for treating bone cancer pain

与本文相关的学术论文