• 不 限
  • 期刊论文
  • 硕博论文
  • 会议论文
  • 报 纸
  • 英文论文
  2. 您的位置
  3. 首页
  4. 会议论文
  5. W/O nanoemulsion-based intranasal drug delivery system of panax notoginseng saponins for brain targe

W/O nanoemulsion-based intranasal drug delivery system of panax notoginseng saponins for brain targe

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：bravehearterdoctor
【摘 要】
：
Panax Notoginseng,a traditional Chinese medicine,has been used for thousands of years to treat cerebrovascular diseases.Being one of the main ingredients of Panax notoginseng saponins (PNS),ginsenosid
【作 者】
：
Zhiying Ding Yue Zhang Na Wen Zhihui Sun Chenhao Li Bingren Zhang 
【机 构】
：
School of Pharmacy,Jilin University,Changchun 130021,China
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
Panax notoginseng saponins (PNS) nanoemulsion intranasal drug delivery brain tar 
下载到本地 , 更方便阅读
下载此文 赞助VIP
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
　　Panax Notoginseng,a traditional Chinese medicine,has been used for thousands of years to treat cerebrovascular diseases.Being one of the main ingredients of Panax notoginseng saponins (PNS),ginsenoside Rg1 (Rg1) (molecular weight =801) is a hydrophilic naturally occurring drug that is hardly transported across the blood-brain barrier.The distribution of PNS in brain is important for cerebrovascular disease.Therefore,developing a novel approaches enhancing the brain delivery of PNS are required for the treatment of cerebrovascular diseases.The nanoemulsion(NE) mediated Intranasal pathway can be an efficacious drug delivery system for brain-targeting delivery [1].
其他文献
PEGylated dendritic diaminocyclohexyl-platinum (Ⅱ) conjugates as pH-responsive drug delivery vehicle
Environmentally-responsive peptide dendrimers loaded with drugs are suitable candidates for cancer therapy.In this study,we report the preparation and characterization of mPEGylated peptide dendrimer-
会议
Solvent-free generation of polycaprolactone composite films with inorganic nanoparticles for localiz
Modern nanoparticle-based drug delivery platforms require further development,both to increase their long-term pharmacological efficiencies as well as to reduce potential side effects.These rely on th
会议
The ATP-binding cassette transporter G1 (ABCG1)is able to mediate cholesterol efflux through lipid r
The ATP-binding cassette transporter G1 (ABCG1)is a member of ATP-binding cassette transporters superfamily.The ABCG1 is known to be able to protect against atherosclerosis,due to the ABCG1 mediating
会议
Succinobucol loaded nanoassembly suppresses lung metastasis of breast cancer by inhibition of VCAM-1
The prevention and treatment of lung metastasis of breast cancer remain a major challenge.The recent finding of vascular cell adhesion molecule-1 (VCAM-1) provides a potential therapeutic target in lu
会议
nanoassemblysuccinobucolcancer metastasisVCAM-1oral deliverybreast cancer
Drug release mechanisms of chemically cross-linked albumin microparticles: effect of the matrix eros
One of the most promising areas of particles is the research and development of new pharmaceutical formulations,being that the main application is aimed towards the drug delivery.Among the various mat
会议
albumindrug deliveryemulsionerosionmicroparticlesdrug release kinetics
Antibacterial ciprofloxacin hydrochloride incorporated PVA/regenerated silk fibroin nanofibers compo
In order to avoid the harmful effects of organic solvents,many water soluble polymers such as polyvinyl alcohol (PVA),polyethylene oxide (PEO),silk fibroin (SF) have been used to fabricate green,Eco f
会议
electrospinningpoly(vinyl alcohol)silk fibroinwound dressingciprofloxacin hy
Long-term release of water-soluble drugs using microsol-electrospun nanofiber sheets
A number of techniques have been developed to incorporate water-soluble drugs into electrospun fibers to achieve sustained drug release [1].However,problems including burst and uncontrolled release st
会议
water-soluble drugmicrosol electrospinningnanofibercore-shell structure
Cell laden and patterned chitosan microgel for micro-scale tissue engineering
Biodegradable and cell laden polymer microgels acting as functional building blocks for microscale tissue engineering have potential application in the construction of complex structures like native o
会议
UV crosslinkable hydrogelcell patterningpatterned hydrogelchitosan microgel
Nanoparticles targeting to osteoblasts for potential intracellular pathogen elimination
Infectious caused by intracellular pathogens,such as viral,bacterial and parasites have been a serious worldwide public health concern and affected millions of people annually.Unlike extracellular pat
会议
intracellulartargetingpaten gen elimination
Rapid detection of rare-event cell by SUPER Dots based diagnostics nano-platform
Non-invasive diagnostic testing of diseases,such as cancer,has the potential to lead to better treatment outcomes and lower healthcare costs [1].However,ten cells or even less need to be found in 10 m
会议
disease diagnosticsupconversionhigh-sensitivitySUPER Dotsintracellular relea