【摘 要】
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The coexistence of chronic obstructive pulmonary disease(COPD)and obstructive sleep apnea syndrome(OSA)is known as overlap syndrome.Globally,the incidence of overlap syndrome in individuals >40 years
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The coexistence of chronic obstructive pulmonary disease(COPD)and obstructive sleep apnea syndrome(OSA)is known as overlap syndrome.Globally,the incidence of overlap syndrome in individuals >40 years of age is estimated at 1#.Although COPD and OSA are pulmonary diseases with specific diagnoses they share similar features,including pathophysiology that involves airway obstruction and the inflammatory response,clinical characteristics,and treatment options.Currently,clinicians lack awareness of these similarities and knowledge and vigilance in overlap syndrome.As reviews on overlap syndrome are scare,this article summarizes and discusses the literature on the pathogenesis and clinical characteristics of overlap syndrome to provide a reference for diagnosis and treatment of the disease.
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