Objective: Sodium ferulate (SF) is sodium salt of ferulic acid which is one of the active ingredients in Radix Angelica Sinensis and Ligusticum chuanxiong hort.It has the effect of refraining endothel
AIM: Investigate the effect of PHF1027 (a formula consists of gypenosides and other two components, data not published) on blood lipid and glucose regulation in mice.METHODS: Fourty four mice were ran
目的:研究三公膏对小鼠的补益作用.方法:对照组小鼠灌胃生理盐水,实验组以样品浸膏1.508g/ (kg.d)剂量灌胃"三公膏",每日给药1次,连续给药5d.观察雄性小鼠与发情期雌鼠交配过程中的捕捉次数及捕捉潜伏期;测定小鼠常压耐缺氧存活时间.结果:观察小鼠交配实验可得,与空白对照组比较,"三公膏"实验组小鼠捕捉潜伏期(P<0.05)明显缩短,捕捉次数(P<0.01)显著提高,小鼠性欲增强,三公膏对
Aim of the study: This paper was to establish a more specific, efficient, and conveniently mathematical kinetic model of the components extracted from one of Chinese herbal formula named BYHWD (Buyang
目的:金钗石斛总生物碱(Dendrobium nobile Lindl.Alkaloids,DNLA)已被证实对糖尿病大鼠、高脂饮食饲养大鼠及肾上腺素性高血糖小鼠有降血糖和降血脂作用.本实验旨在进一步研究DNLA对小鼠肝脏糖脂代谢基因的关键调控因子Sirt1及其调控的相关基因表达的影响.方法:采用雄性KM小鼠,连续8天灌胃DNLA(120 mg/kg、240 mg/kg),分离肝脏,提取总RNA,
Objective: To investigate the effect of SBF on cortical cytoplasm apoptotic factors disturbances induced by complex Aβ25-35 in rats.Methods: The cerebral injuries model was established by rats receive
Objective: This work aims to investigate the protective effect of icaritin (ICT) on amyloid-β peptide (Aβ)-induced neurotoxicity, and then to explore that if this effect of ICT is through increasing A
Objective: To investigate the effects of icariin (ICA) on the proliferation of pulmonary artery smooth muscle cell (PASMC) induced by endothelin-1 (ET-1), and explore its mechanisms.Methods: PASMC fro
Objective: To investigate the protective effects of icariin (ICA), one of active components of epimedium, on Lipopolysaccharide (LPS)-induced dopaminergic (DA) neuronal damage in rats.Methods: Male ra
抑郁症是由多种因素引起的情感障碍性疾病,其特点是发病率高、致死率高和复发率高,给社会带来了严重的经济负担。抑郁症的发病机制复杂,现有研究表明其发病机制主要涉及单胺递质、下丘脑-垂体肾上腺轴功能失调、神经再生障碍和表观遗传学等,但是针对这些机制的治疗药物缺乏治疗效果并伴有副反应。因此,进一步研究抑郁症的发病机制至关重要。