Prediction of fold type is a critical step in protein structure prediction[1].we developed two algorithms,HH-fold and SVM-fold for protein fold type prediction.HH-fold is a template-based fold assignment algorithm using the HMM-HMM alignrment program HHsearch[2].SVM-fold is a support vector machine-based ab-initio modeling algorithm,in which a comprehensive set of features are extracted from three complementary sequence profiles.These two algorithms are then combined,resulting to the ensemble approach TA-fold.TA-fold was evaluated and compared with five recently developed methods on four benchmark datasets.