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5. Biosynthetic mechanism of lanosterol:cyclization

Biosynthetic mechanism of lanosterol:cyclization

来源 :The 15th ICQC International Congress of Quantum Chemistry(第1 | 被引量 : 0次 | 上传用户：pkpm1

【摘 要】

：

Human oxidosqualene cyclase(OSC) plays a key role in cholesterol biosynthesis.It can catalyze the linear-chain 2,3-oxidosqualene to form tetracycliclanosterol,which is the precursor of cholesterol.

【作 者】

：

Nanhao Chen B.Andes Hess Ruibo Wu 

【机 构】

：

School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,P.R.China

【出 处】

：

The 15th ICQC International Congress of Quantum Chemistry(第1

【发表日期】

：

2015年5期

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Human oxidosqualene cyclase(OSC) plays a key role in cholesterol biosynthesis.It can catalyze the linear-chain 2,3-oxidosqualene to form tetracycliclanosterol,which is the precursor of cholesterol.

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