ANKIB1在炎症中的作用和机制

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户:jiangguoliang
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  炎症反应是机体抵御感染和损伤的复杂的级联过程.生物信息学表明,含锚蛋白重复序列和IBR结构域蛋白1(ANKIB1)含有丰富的结构域和模体,如ANK结构域、泛素结合模体(ubiquitin.interacting motif,UIM)、钙调蛋白(calmodulin,CaM)结合模体、肿瘤坏死因子相关因子(tumor necrosis factor receptor-associated factor 6,TRAF6)结合模体等,并且与多种炎症反应相关的信号通路如NF-κB相关.
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